Therapeutic Review:

Jagdish N. Sharma

Does the Kinin System Mediate in Cardiovascular Abnormalities? An Overview
J Clin Pharmacol 2003 43: 1187. [Abstract] [Full Text] [PDF]  

J. T. Wilson, G. Kearns, and M. A. Springer

Role of the Research-Subject Locator (RSL) in the Performance of a Pediatric Drug Trial
J Clin Pharmacol 2003 43: 1196. [Abstract] [Full Text] [PDF]  

Clinical Studies:

L. Michael Prisant, Henry Krum, Barbara Roniker, Scott L. Krause, Kaffa Fakouhi, and Weizhong He

Can Renin Status Predict the Antihypertensive Efficacy of Eplerenone Add-On Therapy?
J Clin Pharmacol 2003 43: 1203. [Abstract] [Full Text] [PDF]  

Drug Metabolism:

Héctor M. Gonzalez, Elba M. Romero T, A. Aaron Peregrina L, Teresa de J. Chávez C, Estanislao Escobar-Islas, Felipe Lozano K, and Carlos Hoyo-Vadillo

CYP2C19- and CYP3A4-Dependent Omeprazole Metabolism in West Mexicans
J Clin Pharmacol 2003 43: 1211. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Donald E. Mager, Sheren X. Lin, Robert A. Blum, Christian D. Lates, and William J. Jusko

Dose Equivalency Evaluation of Major Corticosteroids: Pharmacokinetics and Cell Trafficking and Cortisol Dynamics
J Clin Pharmacol 2003 43: 1216. [Abstract] [Full Text] [PDF]  

Robert R. Henry, Sunder Mudaliar, Neelima Chu, Dennis Kim, Debra Armstrong, Trent T. Davis, Bob An, and Rickey R. Reinhardt

Young and Elderly Type 2 Diabetic Patients Inhaling Insulin with the AERx^® Insulin Diabetes Management System: A Pharmacokinetic and Pharmacodynamic Comparison
J Clin Pharmacol 2003 43: 1228. [Abstract] [Full Text] [PDF]  

Peggy Gandia, Marie-Pierre Bareille, Sylvie Saivin, Anne Pavy Le-Traon, Michel Lavit, Antonio Guell, and Georges Houin

Influence of Simulated Weightlessness on the Oral Pharmacokinetics of Acetaminophen as a Gastric Emptying Probe in Man: A Plasma and a Saliva Study
J Clin Pharmacol 2003 43: 1235. [Abstract] [Full Text] [PDF]  

B. K. Skrumsager, K. K. Nielsen, M. Müller, G. Pabst, P. G. Drake, and B. Edsberg

Ragaglitazar: The Pharmacokinetics, Pharmacodynamics, and Tolerability of a Novel Dual PPAR and Agonist in Healthy Subjects and Patients with Type 2 Diabetes
J Clin Pharmacol 2003 43: 1244. [Abstract] [Full Text] [PDF]  

Jens Teichert, Robert Hermann, Peter Ruus, and Rainer Preiss

Plasma Kinetics, Metabolism, and Urinary Excretion of Alpha-Lipoic Acid following Oral Administration in Healthy Volunteers
J Clin Pharmacol 2003 43: 1257. [Abstract] [Full Text] [PDF]  

Katsutoshi Ogawa, Setsuo Hasegawa, Yuko Udaka, Keinosuke Nara, Shinichi Iwai, and Katsuji Oguchi

Individual Difference in the Pharmacokinetics of a Drug, Pravastatin, in Healthy Subjects
J Clin Pharmacol 2003 43: 1268. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Y. W. Francis Lam, Cara L. Alfaro, Larry Ereshefsky, and Michael Miller

Pharmacokinetic and Pharmacodynamic Interactions of Oral Midazolam with Ketoconazole, Fluoxetine, Fluvoxamine, and Nefazodone
J Clin Pharmacol 2003 43: 1274. [Abstract] [Full Text] [PDF]  

Ranjeev S. Sandhu, Randy P. Prescilla, Thomas M. Simonelli, and David J. Edwards

Influence of Goldenseal Root on the Pharmacokinetics of Indinavir
J Clin Pharmacol 2003 43: 1283. [Abstract] [Full Text] [PDF]  

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