Drug Development:

Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf, Volker Fischer, Lawrence Gan, Scott Grimm, John Kao, S. Peter King, Gerald Miwa, Lan Ni, Gondi Kumar, James McLeod, Scott R. Obach, Stanley Roberts, Amy Roe, Anita Shah, Fred Snikeris, John T. Sullivan, Donald Tweedie, Jose M. Vega, John Walsh, and Steven A. Wrighton

The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective
J Clin Pharmacol 2003 43: 443. [Abstract] [Full Text] [PDF]  

Camilla Buöen, Sture Holm, and Mikael S. Thomsen

Evaluation of the Cohort Size in Phase I Dose Escalation Trials Based on Laboratory Data
J Clin Pharmacol 2003 43: 470. [Abstract] [Full Text] [PDF]  

Mary Ellen Kitler and Nevio Zagaria

Ensuring Supplies of Quality Diethylcarbamazine Citrate (DEC)
J Clin Pharmacol 2003 43: 477. [Abstract] [Full Text] [PDF]  

Therapeutic Review:

Claire M. Lathers, Paul L. Schraeder, and H. Gregg Claycamp

Clinical Pharmacology of Topiramate versus Lamotrigine versus Phenobarbital: Comparison of Efficacy and Side Effects Using Odds Ratios
J Clin Pharmacol 2003 43: 491. [Abstract] [Full Text] [PDF]  

Clinical Trial:

Philip T. Leese, David P. Recker, and Jeffrey D. Kent

The COX-2 Selective Inhibitor, Valdecoxib, Does Not Impair Platelet Function in the Elderly: Results of a Randomized Controlled Trial
J Clin Pharmacol 2003 43: 504. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Vladimir Piotrovsky, Achiel Van Peer, Nancy Van Osselaer, Martin Armstrong, and Jeroen Aerssens

Galantamine Population Pharmacokinetics in Patients with Alzheimer's Disease: Modeling and Simulations
J Clin Pharmacol 2003 43: 514. [Abstract] [Full Text] [PDF]  

Marek Drozdzik, Leszek Domanski, Jerzy Wojcicki, Artur Pudlo, and Piotr Machoy

Effect of Unilateral Nephrectomy on the Pharmacokinetics of Atenolol in Humans
J Clin Pharmacol 2003 43: 524. [Abstract] [Full Text] [PDF]  

Nancy E. Martin, Kathryn R. Collison, Louis L. Martin, Sarah Tardif, Ian Wilding, Heather Wray, and Jeffrey S. Barrett

Pharmacoscintigraphic Assessment of the Regional Drug Absorption of the Dual Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitor, M100240, in Healthy Volunteers
J Clin Pharmacol 2003 43: 529. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Allison W. Wallace, Jennifer M. Victory, and Guy W. Amsden

Lack of Bioequivalence When Levofloxacin and Calcium-Fortified Orange Juice Are Coadministered to Healthy Volunteers
J Clin Pharmacol 2003 43: 539. [Abstract] [Full Text] [PDF]  

Adverse Events:

Michael J. Crook

Isoniazid-Induced Anaphylaxis
J Clin Pharmacol 2003 43: 545. [Abstract] [Full Text] [PDF]  

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